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Great game, confusing at first but there is videos online and I think you can download a beginner tutorial file which will take you through the machanics and basics of the game so you are able to play succesfully. I recommend downloading this, especially because it's free.
The only flaw of getting it on Desura, is the fact it isn't up to date. If you want the latest version, you will have to go over to the OpenTTD website.
reminds me of Left 4 Dead for the NES (mod i found)
Great :D